Microdosing psychedelics has been exploding in popularity over the past couple of years

DosedMovie Documentary Psilocybin Mushrooms
Photo Credit: @DosedMovie on Instagram

People are claiming that it can help with everything from creativity, depression, and ADD/ADHD, to even, apparently, menstrual cramps!  I had been pretty critical of these claims early in their popularity, especially when it comes to clinical depression (the last thing a depressed person needs is to be failed by yet another hyped-up magic bullet), but my mind has changed. More and more people are coming to the forefront to claim microdosing psychedelics, psilocybin in particular, has transformed their lives for the better, including me. Even science is starting to echo some of those claims.

A study by Luisa Prochazkova of the Cognitive Psychology Unit & Leiden Institute for Brain and Cognition at Leiden University, “Exploring the Effect of Microdosing Psychedelics on Creativity in an Open-Label Natural Setting”, published October 25 in the journal Psychopharmacology, looked at microdosing psilocybin (in the form of “truffles”) and found that it helps support divergent thinking. Creativity is an obvious possible outcome of more divergent thinking, but when it comes to depression’s tendency to have us stuck in a negative-psychological loop, divergent thinking can be an incredible advantage to bettering our wellbeing.

As science continues to invest itself in getting good research, the underground culture, already sold on the benefits of microdosing psilocybin, are pushing for what’s next. Now that we know it works (for most people, to some degree), how can we support what it’s doing to help it work even better? Well, one way is to stack psilocybin with other agents.

A stacking formula or “stack” is a term that describes a collection of agents (such as supplements, nutraceuticals, or drugs) that are proposed to have synergistic effects with each other, optimizing a particular result. Stacks are a familiar mainstay of the nootropic or cognitive enhancing culture, in which microdosing psychedelics have taken a prominent seat of influence and popularity.

Paul Stamets presenting his Psilocybin Nootropic Stack at The Spirit Plant Medicine Conference, 2018. Credit: James W. Jesso, 2018

One of the most popular psychedelic microdosing stacking formulas recently circulating the internet is brought to us by world-renown mycologist, Paul Stamets. He calls it his ‘Nootropic Vitamin Complex, Stacking Formula For Epigenetic Neurogenesis.’

Based on the synergistic effects of both lion’s mane and psilocybin mushrooms on brain health, along with the potentials of Niacin (Vitamin B3) to assist in deliverability, Stamets hypothesizes that this stack will help with:

  • creativity
  • cognition
  • post-traumatic stress disorder (PTSD)
  • regeneration of neurons
    • improving auditory and visual neurons
  • citizenship, (yes, generally make you a better member of society as a whole)
  • All forms of neuropathy (nerve damage)

Of course, psilocybin microdosing alone has been shown anecdotally to help with a variety of mental health and mental disorders and increase desirable states of mind from creativity to general enthusiasm about being alive. But Stamets claims that in combination with the other two ingredients of his stack, the power of the psilocybin mushrooms can be amplified and reinforced to make long-term changes in brain structure.

Of course, I needed to give this a try. 

paul austin third wave podcast microdosing
Listen to my podcast interview with Paul Austin, Microdosing For A Better World

My previous experiences with microdosing psilocybin on its own were good, although I noticed that the effect only lasted as long as I stayed on the protocol. The prospect that I might be able to change the structure of my brain to maintain the positive outcomes of microdosing psilocybin without actually having to take it is incredible. Furthermore, the suggestion that this stack might be able to have a long-lasting positive impact on neuropathy and other neurodegenerative issues (such as Alzheimer’s disease) is something that, if true, will be revolutionary for the human species. The loss of our elders to modern agedness’ prevalence of neurological decline is not only personal disturbing but for anyone involved directly, as well as society as a whole. This is, truly, something incredible, but, does it work? Well, there is only one way to find out, at least for myself, and that’s to give it a try.

I started back experimenting with the Stamets Microdosing Stack and Protocol in November of 2018 and continued until the time of posting the video below, end of January 2019, with some breaks in the mix. Besides personal and professional curiosity, my primary interest was in whether or not this stack would help me with my ADD/ADHD, mental health, and whatever consequences might be lingering around after the four concussions I have suffered in my life.

My report from that experiment is contained in the video below.

The video also discusses:

  • the Stacking Formula’s ingredients and dosage
  • the theory of its method of action
  • my dosing protocol
  • my reasoning, including an in-depth exploration of how my ADD/ADHD manifests in my daily life as an entrepreneur
  • the results
  • important caveats that might skew results
  • three month follow-up after a break from the protocol

Watch My Video Report On The Paul Stamets Stack


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